Basic Information
VIS ID
TVIS44011927
Fusion event
HTLV-1-LOC105375545 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q34
Reference genome
GRCh37/hg19
Start
142976965/143279872 (Hg38)
End
142976965/143279872 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105375545
Nearest miRNA
hsa-mir-10399/Upstream/805269; hsa-mir-153-2/Downstream/102814;
Nearest TSS
ENST00000635602/Upstream/16376; ENST00000482420/Downstream/85;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/424448, chr7-CpG: 81/Downstream/8082
Nearby gene
TMEM139(+5027) ;
Upstream sequence
CAATGTTGCTCACCTATGTCATGATAAACCATTTATCCACCTTCCTTACACATTTTGGAGAAGCTGTGACTAAGGCAATTTCTGAAGGGGAAAACACACC
Downstream sequence
CAGCTGAATTAAAAGGTCAAGGTTCTGAGTTTCCTTCTAACTAAAGaaatcgtgtactttctctgagcttgtttcctctgtaaaatgaaagtgataatca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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