Basic Information
VIS ID
TVIS44011937
Fusion event
HTLV-1-LOC107986895 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
87784955/86772727 (Hg38)
End
87784955/86772727 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107986895
Nearest miRNA
hsa-mir-12123/Upstream/6531254; hsa-mir-10400/Downstream/4432758;
Nearest TSS
ENST00000518652/Upstream/6792; ENST00000517748/Downstream/93715;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/257683, chr8-CpG: 25/Downstream/1101216
Nearby gene
CNGB3(-29052) ;
Upstream sequence
GAAGGATAATATTTTCCTCTGAATAATTTCAATTTTTAATCAATATCCTACATCTGCTATTTTAATAACACATTTTAAAATGATTGGATTTAAATATACT
Downstream sequence
CACTTAAATTTCCTCACCTAAAGATGTACAGATGCTTCTTGAAAGCTCTTCCTGATGATTTCATACACACACATACACATACACATGTATACATGCATGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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