Basic Information
VIS ID
TVIS44011940
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
20320866/20320868 (Hg38)
End
20320866/20320868 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA9C
Nearest miRNA
hsa-mir-101-2/Upstream/1747489; hsa-let-7a-1/Downstream/90280;
Nearest TSS
ENST00000422679/Upstream/394774; ENST00000604036/Downstream/42701;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/386039, chr9-CpG: 167/Downstream/299557
Nearby gene
MLLT3(-20797) ;
Nearest cancer related gene
MLLT3(OG, -20797) ;
Upstream sequence
TTTCAGGCAATTTGGGAGTGAAAGGCCAGCAGGCAGCTTTATCTTGAAGACTGTTCAGCTCCACAGGGTGACAGATTCTCCCACCAACCATGTCTCTGTC
Downstream sequence
AGCCTCAGCCCAAGAGAAAATTGAGCTGAATAAGAGAGGTCTCAGTGGAAATTATATTGGAAAGACTCACCATAATGGCTTCCTGAAAAAAATACATAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate