VISDB Viral Integration Site DataBase

VIS ID

TVIS44011983

Fusion event

HTLV-1-TIMM50 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr19

Cytoband

q13.2

Reference genome

Start

End

39974455/39483815 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-7-5p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-324-5p ; hsa-mir-222-3p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6090 ; hsa-mir-6827-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-544b ; hsa-mir-5690 ; hsa-mir-4293 ; hsa-mir-890 ; hsa-mir-640 ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-4680-5p ; hsa-mir-150-5p ; hsa-mir-1224-3p ; hsa-mir-186-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6778-3p ; hsa-mir-4635 ; hsa-mir-3653-5p ; hsa-mir-6818-3p ; hsa-mir-4684-5p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-339-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-6732-3p ; hsa-mir-18a-5p ; hsa-mir-18b-5p ; hsa-mir-3151-5p ; hsa-mir-4735-3p ; hsa-mir-486-3p ; hsa-mir-6721-5p ; hsa-mir-7-1-3p ; hsa-mir-7-2-3p ; hsa-mir-873-5p ; hsa-mir-92a-2-5p ; hsa-mir-935 ; hsa-mir-106a-3p ; hsa-mir-122-5p ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3135b ; hsa-mir-3650 ; hsa-mir-3652 ; hsa-mir-3666 ; hsa-mir-3689d ; hsa-mir-4295 ; hsa-mir-4430 ; hsa-mir-454-3p ; hsa-mir-504-3p ; hsa-mir-1182 ; hsa-mir-1267 ; hsa-mir-129-5p ; hsa-mir-3672 ; hsa-mir-367-5p ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-6812-3p ; hsa-mir-6864-3p ; hsa-mir-8055

Nearest miRNA

hsa-mir-10395/Upstream/74137; hsa-let-7e/Downstream/345901;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/2737, chr19-CpG: 63/Downstream/14942

Upstream sequence

ATTGTTTCAAACTGGGCAGTTGTAGAATCATGCTGGCTTCAACAAATCAGTATGCTGATTTAAATTGGGCAGGTACATCTGCAGTTTTAAAGTGTATATG

Downstream sequence

TTTACTAGCCTAACTGGTTTCAATATTGTGGtttatttttatttttatttttttttgagacatagtcttgctctgttgcctaggctggagtgcagtgatg