Basic Information
VIS ID
TVIS44012004
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
3181920/3181806 (Hg38)
End
3181920/3181806 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-4277/Upstream/1472938; hsa-mir-10397/Downstream/3646047;
Nearest TSS
ENST00000502646/Upstream/3971; ENST00000512521/Downstream/271010;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/314915, chr5-CpG: 22/Downstream/6179
Nearby gene
LINC01377(No orient, 574)
Upstream sequence
TAGTGCAGAGAGCATCTGAATCCTGTAGTGTGTTGATTTGAATAAAGCAAGGAACGCTCTTCCTACCGTGATGGCCTCTTGCAGGGCTGAACGGGAAAGG
Downstream sequence
GACGCGGCACAGTCTGGCAGTGCGTGGGAGCAAACGAAACCTGCACAAAGGGAGGCGGAAGAAAACAGGGAGGGATCTGAACACACACTCAATAGGGATC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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