Basic Information
VIS ID
TVIS44012014
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
43933668/43965931 (Hg38)
End
43933668/43965931 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-10398/Upstream/531311; hsa-mir-10524/Downstream/288275;
Nearest TSS
ENST00000381078/Upstream/113598; ENST00000448947/Downstream/34649;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/193816, chr6-CpG: 94/Downstream/36256
Nearby gene
LINC01512(No orient, 27724)
Upstream sequence
TGCCTTTCTGAGACCTGAGGGcagtagtgtgttggagccaatctgctgcagcttggacagttgtaaacttttcttcccaactgcttatccattgacttca
Downstream sequence
ggttggtagtctgaagtcagccatggtgggagtatttacaccacagaaattggcaaatgctacaaaagaggactttttcacccagagagctggtcgtgaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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