Basic Information
VIS ID
TVIS44012067
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
23018687/21646366 (Hg38)
End
23018687/21646366 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/2960202; hsa-mir-155/Downstream/1432918;
Nearest TSS
ENST00000624081/Upstream/79603; ENST00000425979/Downstream/39963;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/648121, chr21-CpG: 28/Downstream/3715428
Nearby gene
LINC00317(-76926) ;
Upstream sequence
gccatattttcaaagtaatttttctgtattaacttctttctttctttctctactcttatgactcccagcactgacttatttttgaatatccacactcatt
Downstream sequence
tgttccaatgttcatttcacatctccacattttttccagaggcaccttgaattaaacctatccaaaagtgaatccatgaaactttatcaacagtctttca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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