Basic Information
VIS ID
TVIS44012075
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
66047630/65473498 (Hg38)
End
66047630/65473498 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA13B
Nearest miRNA
hsa-mir-1297/Upstream/4273618; hsa-mir-1267/Downstream/492832;
Nearest TSS
ENST00000623511/Upstream/1397487; ENST00000437777/Downstream/392676;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1628952, chr13-CpG: 92/Downstream/1756878
Nearby gene
LINC01052(No orient, 392549)
Upstream sequence
TTGTGTCTCATTACACAGCAGGGCATGGAATGAGCAATAAACATGTTACCATAAGTTTTGTACTGAATGATTATTTAATTAAATCACAACTTTTAAAACA
Downstream sequence
TTTCCATTCTGTGTCACCCTTGGGTTTGACATCTTATATTCATATATCTATTTTATCAATCTATCTACAATGAATCACAAAACCATGCTGAAAAAATTGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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