Basic Information
VIS ID
TVIS44012079
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q16.2
Reference genome
GRCh37/hg19
Start
99449809/99001933 (Hg38)
End
99449809/99001933 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/977312; hsa-mir-1202/Downstream/122676;
Nearest TSS
ENST00000381078/Upstream/53927; ENST00000418945/Downstream/282279;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/53840, chr6-CpG: 99/Downstream/347399
Nearby gene
FBXL4(-53927) ;
Upstream sequence
aaaacccactatgtgccaggcattgtgctaggtacaggaaataatattaacaagaAATCATTTTAATGCTTACCTGTACACCATTAATTCAGTTAAAGTC
Downstream sequence
TATGTCAACATCCTTCCACCCATAGCAAGCTACTCTTACTATGTGTGTGAGGGGCACAGTTTCCCACAGGAGATGGATCCTGTTGGGGGAGGTAACTGCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate