Basic Information
VIS ID
TVIS44012121
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
60758799/59846240 (Hg38)
End
60758799/59846240 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/16949965; hsa-mir-10400/Downstream/1868548;
Nearest TSS
ENST00000518652/Upstream/244836; ENST00000531077/Downstream/203347;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/726053, chr8-CpG: 14/Downstream/327326
Nearby gene
CA8(-342624) ;
Upstream sequence
acaaATtaaatcaccaactcaaaaagctaaaaagttaaccaaggaaataaagagaaaacataagaaagaaaataataaagattaaaataaaatttgttga
Downstream sequence
gttagaaaatagaaaaataattgaactaaaattaacaaaATAGATCATCGGGTAACTTGAGAATAAAGGGAGGAAAGGACAAATTCACAGAATTTAAAAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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