Basic Information
VIS ID
TVIS44012122
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
123565552/122553313 (Hg38)
End
123565552/122553313 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA8C ; FRA8E
Nearest miRNA
hsa-mir-12123/Upstream/3228048; hsa-mir-10400/Downstream/662475;
Nearest TSS
ENST00000518652/Upstream/63498; ENST00000607393/Downstream/140793;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/913164, chr8-CpG: 223/Downstream/226817
Upstream sequence
CCATGTAAGGGAATTAAAGATGTTTGGTATTATTTGGTAGTAGAGTTAAAGTCAGAagtgattgggaataaaactggaaaaataaaaaggaaccaggtta
Downstream sequence
taaagagccttgtaagtcatgtaaagaAGTTTGAGCTGTATACCGTACGTAACATTATCAAATTTATATTCTAGAAcagtagtccccaacctttttgaca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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