VISDB Viral Integration Site DataBase

VIS ID

TVIS44012136

Fusion event

HTLV-1-PTPN4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q14.2

Reference genome

Start

End

120720215/119962639 (Hg38)

Orient

+

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-148a-3p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-4670-3p ; hsa-mir-4709-5p ; hsa-mir-520h ; hsa-mir-3973 ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4803 ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-142-5p ; hsa-mir-5590-3p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-106a-5p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-454-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-489-3p ; hsa-mir-3144-3p ; hsa-mir-376a-5p ; hsa-mir-4766-5p ; hsa-mir-2054 ; hsa-mir-627-3p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-8084 ; hsa-mir-5089-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-4707-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-4698

Nearest miRNA

hsa-mir-1285-2/Upstream/6241271; hsa-mir-10b/Downstream/7460898;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/202205, chr2-CpG: 102/Downstream/50182

Upstream sequence

aaacatttttaaaaattGGAGAACATGAATCCATATGtatataattttatttattatttatttatatCAATATCAGGTTAAATGTCACCAATATTGGCCA

Downstream sequence

GAACCCACAGGCAGTTCATCTTATGGATGCTACCAAGTTACCTGCCACTCTGAAGAAGGAAACACTGCCTATATCTTCAGGAAGATGACCCTATTTAACC