Basic Information
VIS ID
TVIS44012149
Fusion event
HTLV-1-PRR7-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
GRCh37/hg19
Start
176872569/177445568 (Hg38)
End
176872569/177445568 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA5G
Target gene
PRR7-AS1
Nearest miRNA
hsa-mir-10397/Upstream/816068; hsa-mir-1229/Downstream/2352710;
Nearest TSS
ENST00000502646/Upstream/988; ENST00000507881/Downstream/877;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/9303, chr5-CpG: 116/Downstream/780
Upstream sequence
aaatgagtccaaaaagaatcattcatggagttgtttgcttgtattttgctcaaatgatggggaaggaattggggttccgttttcctccagggatagatgg
Downstream sequence
caggatatgagcctagggctgttggggttgtcctcgctacttcttggggtgagcttgcctgagagtgatgcaaacagaagcagatacgtgcctgacacca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate