VISDB Viral Integration Site DataBase

VIS ID

TVIS44012152

Fusion event

HTLV-1-DENND5B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr12

Cytoband

p11.21

Reference genome

Start

End

31736633/31583699 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1298-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-4276 ; hsa-mir-2053 ; hsa-mir-569 ; hsa-mir-3152-3p ; hsa-mir-3650 ; hsa-mir-493-3p ; hsa-mir-5190 ; hsa-mir-4705 ; hsa-mir-5094 ; hsa-mir-8084 ; hsa-mir-4724-5p ; hsa-mir-3121-3p ; hsa-mir-655-3p ; hsa-mir-429 ; hsa-mir-374c-5p ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1304-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-1251-5p ; hsa-mir-329-5p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-1914-5p ; hsa-mir-660-3p ; hsa-mir-6890-3p ; hsa-mir-1306-5p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-486-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-4438 ; hsa-mir-4279 ; hsa-mir-122-3p ; hsa-mir-6833-3p ; hsa-mir-6873-3p ; hsa-mir-4768-5p ; hsa-mir-6868-3p ; hsa-mir-6853-3p ; hsa-mir-3182 ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-4290 ; hsa-mir-4740-3p ; hsa-mir-4687-5p ; hsa-mir-449b-3p ; hsa-mir-6856-3p ; hsa-mir-8485 ; hsa-mir-4662a-5p ; hsa-mir-582-5p ; hsa-mir-600 ; hsa-mir-323b-3p ; hsa-mir-708-3p ; hsa-mir-144-3p ; hsa-mir-101-3p ; hsa-mir-93-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/5709620; hsa-let-7i/Downstream/10740001;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/257251, chr12-CpG: 202/Downstream/6127

Upstream sequence

cctgggaggcagaggttgcagtgagccgagatcacgctactgcactccagcccgggcaacagagcaagactgtgtctgggaaaaaacaaaaacaaaaaca

Downstream sequence

aaaacaaacaacaacaacaacaagaatttagcacagtgtctggcatgtggaaagcactctataaatgttagctattTTACTATTTCATCACAGATTCTTA