Basic Information
VIS ID
TVIS44012171
Fusion event
HTLV-1-LOC105378813 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
81633738/81168053 (Hg38)
End
81633738/81168053 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
LOC105378813
Nearest miRNA
hsa-mir-101-1/Upstream/4107851; hsa-mir-11399/Downstream/3965741;
Nearest TSS
ENST00000473358/Upstream/526769; ENST00000642971/Downstream/41781;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/836852, chr1-CpG: 281/Downstream/632260
Nearby gene
LOC101927434(No orient, 345827)
Upstream sequence
TAAGCCATGTTGTATCTTATTAGCAATATACTTCATTGTTAATGGAAGTTTGATAAAGACTTCCATGGAACAGGCTTCCAAATATGTGGAAGTCAATAGT
Downstream sequence
TACATAAAAAGATATACAAAGAAAGAAAATGTATTCTTCCTAGAATTTGAAAGATAATAGCAAGGACttcattgagctcctattatgtgtcagttgctac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate