Basic Information
VIS ID
TVIS44012195
Fusion event
HTLV-1-ADAMTS9-AS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
64833865/64848190 (Hg38)
End
64833865/64848190 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
ADAMTS9-AS2
Nearest miRNA
hsa-let-7g/Upstream/4230320; hsa-mir-12124/Downstream/2377274;
Nearest TSS
ENST00000440867/Upstream/160190; ENST00000481004/Downstream/326768;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/159909, chr3-CpG: 63/Downstream/508338
Nearest cancer related gene
ADAMTS9-AS2(TSG, No orient, 0)
Upstream sequence
ATAACTCTAAAAAATACTGTCCCAAAGTAATTTGATACGTGAAAATCATTATCTCCCAACACTTCTTACTGCTGCAGCTCCCACTTCCTTGTGCTAGTCA
Downstream sequence
TTATTTAACAGGTTAAAGAGCACAGTCTTTTGGTTATTATGCAAATATTTTTTGAGTGCTGACTATACCTTTCCACCAAGATGTATGTTAGGGTATCCCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate