Basic Information
VIS ID
TVIS44012241
Fusion event
HTLV-1-LOC107985366 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.3
Reference genome
GRCh37/hg19
Start
235114085/234978338 (Hg38)
End
235114085/234978338 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
LOC107985366
Nearest miRNA
hsa-mir-101-1/Upstream/671799; hsa-mir-1537/Downstream/211696;
Nearest TSS
ENST00000473358/Upstream/8276; ENST00000489692/Downstream/2466;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/367060, chr1-CpG: 30/Downstream/125901
Nearby gene
LOC101927851(No orient, 14339)
Upstream sequence
CCAGAGGACTCAACAAACTCCAGGCATACCAAGTCCAGAAGCCGAGTCCAGAGCTGACAGCCTATTCCCATCTCTATCTCCCACGGAGCTGCAGAGATCA
Downstream sequence
TTAGGGAACTAACGTGGCCACTGCTTCATGCCCACAGAGGCCCACCAGCTCTTTCCTAGAGCAGAACCACCGTGCAGAGAGGTGAGGCACTCCCAGATGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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