Basic Information
VIS ID
TVIS44012277
Fusion event
HTLV-1-LINC02210-CRHR1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
43801632/45724266 (Hg38)
End
43801632/45724266 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02210-CRHR1
Nearest miRNA
hsa-mir-1180/Upstream/248831; hsa-mir-10226/Downstream/1248751;
Nearest TSS
ENST00000595228/Upstream/102340; ENST00000580955/Downstream/8711;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/103296, chr17-CpG: 203/Downstream/59052
Upstream sequence
ATTCCTGCCTTCTTTGCCTACACTAGCCCATGAGCACTTCACCCATGCTAAGCCATCTTCGGCCCAAATGGCCCTTGAGCATGCATTTGAAAAACAGGTG
Downstream sequence
GAAGATAAAACAAGAAGCATgcattggttttgcaggtggaagacctagatttcatgtcctgccagttactaattgtgtggtcctgagtaggtctcctcac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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