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Viral Integration Site DataBase
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TVIS44012305
Basic Information
VIS ID
TVIS44012305
Fusion event
HTLV-1-PCYT1A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
GRCh37/hg19
Start
196010265/196283394 (Hg38)
End
196010265/196283394 (Hg38)
Orient
+
Location type
Intronic
Target gene
PCYT1A
miRNAs that regulate target gene
hsa-let-7b-5p
;
hsa-mir-26a-5p
;
hsa-mir-6778-5p
;
hsa-mir-4298
;
hsa-mir-1302
;
hsa-mir-7106-5p
;
hsa-mir-7154-3p
;
hsa-mir-5004-5p
;
hsa-mir-5681a
;
hsa-mir-4756-5p
;
hsa-mir-4739
;
hsa-mir-1321
;
hsa-mir-5096
;
hsa-mir-5587-5p
;
hsa-mir-6855-5p
;
hsa-mir-3170
;
hsa-mir-197-3p
;
hsa-mir-6832-5p
;
hsa-mir-6801-5p
;
hsa-mir-193b-5p
;
hsa-mir-1273f
;
hsa-mir-484
;
hsa-mir-3155b
;
hsa-mir-3155a
;
hsa-mir-6890-5p
;
hsa-mir-4713-5p
;
hsa-mir-2116-3p
;
hsa-mir-532-3p
;
hsa-mir-150-5p
;
hsa-mir-4264
;
hsa-mir-186-3p
;
hsa-mir-6849-3p
;
hsa-mir-622
;
hsa-mir-1226-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
Nearest miRNA
hsa-let-7g/Upstream/400999; hsa-mir-4797/Downstream/1010484;
Nearest TSS
ENST00000440867/Upstream/12853;
ENST00000420226/Downstream/3869;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/74992
,
chr3-CpG: 76/Downstream/3983
Upstream sequence
gcctgggcaacaaggcaagacttggtctcaaaaaataaataaataaataaatagaaagaaaGGAGGGAAAAGACACACACAGAAAGCCTGCTATTAATAT
Downstream sequence
ATATCTATTAACCTGGTTTACGAATGGTAAAATACAGGTAATTCAATTATTTACATTAATGAATAAGGTAGGTAACAAACCTAAAAGAATGCCAAATATG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL215
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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