VISDB Viral Integration Site DataBase

VIS ID

TVIS44012313

Fusion event

HTLV-1-IL6ST integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr5

Cytoband

q11.2

Reference genome

Start

End

55280983/55985155 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-590-3p ; hsa-mir-335-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-615-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-302c-3p ; hsa-mir-512-3p ; hsa-mir-4501 ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-4789-5p ; hsa-mir-6074 ; hsa-mir-4729 ; hsa-mir-4661-5p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-4650-3p ; hsa-mir-1303 ; hsa-mir-5589-3p ; hsa-mir-4272 ; hsa-mir-548p ; hsa-mir-3924 ; hsa-mir-4473 ; hsa-mir-6073 ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-4328 ; hsa-mir-7852-3p ; hsa-mir-6507-3p ; hsa-mir-8054 ; hsa-mir-548l ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-223-3p ; hsa-mir-142-3p ; hsa-mir-520f-3p ; hsa-mir-1277-5p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-190b ; hsa-mir-190a-5p ; hsa-mir-511-3p ; hsa-mir-4766-3p ; hsa-mir-3941 ; hsa-mir-3908 ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-5706 ; hsa-mir-4782-5p ; hsa-mir-516b-5p ; hsa-mir-488-5p ; hsa-mir-4778-5p ; hsa-mir-2355-3p ; hsa-mir-676-3p ; hsa-mir-6820-3p ; hsa-mir-3164 ; hsa-mir-3118 ; hsa-mir-134-5p ; hsa-mir-3607-5p ; hsa-mir-3177-5p ; hsa-mir-4252 ; hsa-mir-20b-3p ; hsa-mir-3137 ; hsa-mir-449b-3p ; hsa-mir-892a

Nearest miRNA

hsa-mir-10397/Upstream/476229; hsa-mir-103a-1/Downstream/2544888;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/163017, chr5-CpG: 107/Downstream/9352

Upstream sequence

agatattctggcctttattagaaaatggatttacgcattattttcttgtatgcttgtcttttcattcttttaacagtatcttttgacgaataggaggttt

Downstream sequence

aattttaataaagttcaattcatcaatttgtgtttttgatgtatctaagaagtctttgcttaatctaaaatcataaagggcccgacgcagtagctcacac