VISDB Viral Integration Site DataBase

VIS ID

TVIS44012342

Fusion event

HTLV-1-ZFYVE26 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr14

Cytoband

q24.1

Reference genome

Start

End

68253758/67787041 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-340-5p ; hsa-mir-124-3p ; hsa-mir-18b-5p ; hsa-mir-92a-3p ; hsa-mir-17-5p ; hsa-mir-660-5p ; hsa-mir-1180-5p ; hsa-mir-7114-3p ; hsa-mir-218-5p ; hsa-mir-4276 ; hsa-mir-548aw ; hsa-mir-7973 ; hsa-mir-4771 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-3613-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-3714 ; hsa-mir-4796-3p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-548an ; hsa-mir-142-5p ; hsa-mir-5590-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-106a-5p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-520a-3p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-520e ; hsa-mir-372-3p ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-302e ; hsa-mir-373-3p ; hsa-mir-520f-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-130a-3p ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-3154

Nearest miRNA

hsa-mir-208a/Upstream/345111; hsa-mir-1185-1/Downstream/4729779;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/111876, chr14-CpG: 40/Downstream/841257

Upstream sequence

aagacaaacaccacatgttctcacttatgtgtgggatccaaaaatcaaaataactgaattcatggagatagagaatagaaggatggttaccagaggctgg

Downstream sequence

gaaggtagtaaggggtgggggaagatggagatggttaatgagtataaaaaatagttagaggccgggtgtggtggctcacacctgtaatcccagcactttg