Basic Information
VIS ID
TVIS44012356
Fusion event
HTLV-1-LOC105375538 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q34
Reference genome
GRCh37/hg19
Start
141213042/141513242 (Hg38)
End
141213042/141513242 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105375538
Nearest miRNA
hsa-mir-10399/Upstream/2469085; hsa-mir-11400/Downstream/961285;
Nearest TSS
ENST00000635602/Upstream/59; ENST00000492693/Downstream/37947;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/438482, chr7-CpG: 59/Downstream/37971
Nearby gene
TMEM178B(No orient, 32863)
Upstream sequence
ttcgcaatggaggagaaacacagtagaaggatcctggatacataagtcaccacatggaagacagccaccaggagagatgcctgactcacattggactatc
Downstream sequence
atgtggacaagaaataaaatgttattgtgttgagacactgtgctttagagactgtttataagttagcattagtatatctttacAGGGGAAAAATAACTTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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