Basic Information
VIS ID
TVIS44012362
Fusion event
HTLV-1-LINC01924 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
61831258/64164024 (Hg38)
End
61831258/64164024 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC01924
Nearest miRNA
hsa-mir-1-2/Upstream/5712866; hsa-mir-5011/Downstream/2917560;
Nearest TSS
ENST00000575820/Upstream/7809; ENST00000578545/Downstream/96031;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/161003, chr18-CpG: 88/Downstream/1586576
Upstream sequence
AAAAAATAATCAAATATATGGTAGATAGTAAGGGTACCTTATGTCTGCAAAAGTCCACATTCTCCTGGAATACTACATCAGCAGTAGCAGGAAGGACACC
Downstream sequence
TTTTACACTTCAGAAATGCAGAGAAATTGCTGTTGGGTAGACAATTGCTGGAGATATATTGAAATAAGCCTTATGATCTCCACTGAGATGAGAGACAAGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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