Basic Information
VIS ID
TVIS44012367
Fusion event
HTLV-1-LOC105379412 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
140117515/139196361 (Hg38)
End
140117515/139196361 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105379412
Nearest miRNA
hsa-mir-12113/Upstream/13689054; hsa-mir-1305/Downstream/4147099;
Nearest TSS
ENST00000502981/Upstream/19143; ENST00000482087/Downstream/83977;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/17679, chr4-CpG: 41/Downstream/83549
Nearby gene
ELF2(-56885) ;
Upstream sequence
tcttacctcggcctcccaaagtgctgagattataggcatgagccaccatgacaggccCCTTGTATCCTAAtgtaaaccaaaaagtgtctgagacagatct
Downstream sequence
caattgatttagaggtttattctgccagggttgagaatgttcctgggaagaagaaacagaagttcagtagtactcgtggcctgtgctttttccaaagagg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate