Basic Information
VIS ID
TVIS44012393
Fusion event
HTLV-1-AKR1C6P integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
4933213/4891021 (Hg38)
End
4933213/4891021 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
AKR1C6P
Nearest miRNA
hsa-mir-5699/Upstream/899762; hsa-mir-107/Downstream/1261175;
Nearest TSS
ENST00000439456/Upstream/51237; ENST00000476100/Downstream/72232;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/64416, chr10-CpG: 54/Downstream/521447
Upstream sequence
TGAGTCCGTAAAGATAAACTATCCCCAGGTTAAAGAGCCAAGGCATGGCAAAAGCAATACTTCATGAGAGTCTTCTTTGCAGTCCTCAATGGTACACACC
Downstream sequence
ATGTTTCTTTTGTGTTGGGAAACAATCCTACAACTTTTATAACATTCTTCACCAGGAACCACTGAGATGTGCCCTTGTAGGTCTGGAGTGTTTGATCCAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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