VISDB Viral Integration Site DataBase

VIS ID

TVIS44012425

Fusion event

HTLV-1-MDM4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

q32.1

Reference genome

Start

End

204491649/204522521 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-191-5p ; hsa-mir-9-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-let-7b-5p ; hsa-mir-144-5p ; hsa-mir-361-5p ; hsa-mir-3074-3p ; hsa-mir-3689a-5p ; hsa-mir-3689b-5p ; hsa-mir-3689e ; hsa-mir-3689f ; hsa-let-7a-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-mir-98-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-331-5p ; hsa-mir-1272 ; hsa-mir-3924 ; hsa-mir-3927-3p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-4650-3p ; hsa-mir-6755-5p ; hsa-mir-6831-5p ; hsa-mir-34c-5p ; hsa-mir-449a ; hsa-mir-449b-5p ; hsa-mir-485-5p ; hsa-mir-6884-5p ; hsa-mir-7-1-3p ; hsa-mir-7-2-3p ; hsa-mir-3065-5p ; hsa-mir-3529-3p ; hsa-mir-183-5p ; hsa-mir-661 ; hsa-mir-4459 ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-6747-5p ; hsa-mir-608 ; hsa-mir-4664-5p ; hsa-mir-4651 ; hsa-mir-342-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6087 ; hsa-mir-1247-3p ; hsa-mir-6890-5p ; hsa-mir-550b-2-5p ; hsa-mir-203b-3p ; hsa-mir-1227-3p ; hsa-mir-4445-5p ; hsa-mir-6766-3p ; hsa-mir-4782-3p ; hsa-mir-219a-5p ; hsa-mir-508-3p ; hsa-mir-4679 ; hsa-mir-17-3p ; hsa-mir-5572 ; hsa-mir-4260 ; hsa-mir-450a-2-3p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-4709-3p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-2052 ; hsa-mir-542-3p ; hsa-mir-486-3p ; hsa-mir-122-5p ; hsa-mir-3659 ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-7515 ; hsa-mir-494-3p ; hsa-mir-3120-5p ; hsa-mir-6743-5p ; hsa-mir-4688 ; hsa-mir-3154 ; hsa-mir-543 ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-548au-3p ; hsa-mir-202-3p ; hsa-mir-4678 ; hsa-mir-3178 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6499-5p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-1180-3p ; hsa-mir-6850-3p ; hsa-mir-887-3p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-1252-3p ; hsa-mir-141-3p ; hsa-mir-1827 ; hsa-mir-200a-3p ; hsa-mir-200a-5p ; hsa-mir-200b-5p ; hsa-mir-3148 ; hsa-mir-3529-5p ; hsa-mir-3609 ; hsa-mir-3662 ; hsa-mir-374c-3p ; hsa-mir-379-5p ; hsa-mir-3944-5p ; hsa-mir-4451 ; hsa-mir-4470 ; hsa-mir-4661-3p ; hsa-mir-4668-5p ; hsa-mir-4704-3p ; hsa-mir-4716-3p ; hsa-mir-4761-5p ; hsa-mir-499a-3p ; hsa-mir-499b-3p ; hsa-mir-545-3p ; hsa-mir-548ac ; hsa-mir-548ah-5p ; hsa-mir-548as-3p ; hsa-mir-548bb-3p ; hsa-mir-548d-3p ; hsa-mir-548h-3p ; hsa-mir-548z ; hsa-mir-625-5p ; hsa-mir-651-5p ; hsa-mir-6758-3p ; hsa-mir-6794-5p ; hsa-mir-6873-3p ; hsa-mir-876-3p ; hsa-mir-942-5p ; hsa-mir-3122 ; hsa-mir-3913-5p ; hsa-mir-433-3p ; hsa-mir-450a-1-3p ; hsa-mir-514a-3p ; hsa-mir-514b-3p ; hsa-mir-544b ; hsa-mir-6078 ; hsa-mir-6513-5p ; hsa-mir-7112-5p ; hsa-mir-7162-3p ; hsa-mir-887-5p

Nearest miRNA

hsa-mir-101-1/Upstream/2519285; hsa-mir-1182/Downstream/925781;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/5818, chr1-CpG: 100/Downstream/162483

Nearest cancer related gene

MDM4(OG, No orient, 0)

Upstream sequence

acaatcttgctctgtcaccaggctgtagtgcagtggcacgatctcggctcactgcaacctccgcttcccaagttcaggcgattctcctgtctcagcctcc

Downstream sequence

cgagtagttgggactacaggcgtgtgccaccacacctggctaatttttgtatttttagtagagacggtttcaccattttggccaggatagtcttgatctc