Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene94569552944368089447968294480242944814219448162994482077944760809447649294482087944822369448410794484256944796479447973194503180
Basic Information
VIS ID
TVIS44012462
Fusion event
HTLV-1-DCT integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
95155434/94503180 (Hg38)
End
95155434/94503180 (Hg38)
Orient
-
Location type
Intronic
Target gene
DCT
Nearest miRNA
hsa-mir-1297/Upstream/2012960; hsa-mir-1267/Downstream/1924049;
Nearest TSS
ENST00000623511/Upstream/23498; ENST00000376958/Downstream/78009;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1274556, chr13-CpG: 59/Downstream/46126
Nearby gene
DCT(-23498) ;
Upstream sequence
tgaaaatacagttaggttgggtgcggtggctcatgcctataatcccagcactttgggaggccaagggggcatggattgcttgagtccaggagttcaacgc
Downstream sequence
cagcctgggaaacatagcaaaaaccccatctctactaaaaatacaaaaaattagctgggcatggtggtgcatgcctgtagtcccagctactcaggaagct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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