Basic Information
VIS ID
TVIS44012480
Fusion event
HTLV-1-LOC107986829 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
100114582/100516959 (Hg38)
End
100114582/100516959 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7F
Target gene
LOC107986829
Nearest miRNA
hsa-mir-10525/Upstream/160238; hsa-mir-10399/Downstream/351077;
Nearest TSS
ENST00000635602/Upstream/7242; ENST00000477022/Downstream/22252;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/22984, chr7-CpG: 63/Downstream/21866
Nearby gene
NYAP1(No orient, 22158)
Upstream sequence
cactctgttgcccacagtggagtacagaggcacaaccacagctcatcacagcctcaaacccacaggcacggatggacacagtggctcatgcctgtaatcc
Downstream sequence
cagcactttgggaggccaaagtgggtggaccacctgaggtcaacagtttgagaccagcctgaccaacatggttaaaccccgtctctactaaaaaaaaaaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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