Basic Information
VIS ID
TVIS44012502
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.3
Reference genome
End
127288067/126530490 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-1285-2/Upstream/12809122; hsa-mir-10b/Downstream/893047;
Nearby gene
GYPC(+125444) ;
Upstream sequence
AACACCCAGAAAGGTCCAGATCTGGTGTACTGGTGACTCAGTTCGCTCTCTGGAGTAAGTAGGTAGTGTATTAAGCCTGGTCAATCAAAATTGAGGATCC
Downstream sequence
TTGGTGACTTCAAATTTATCCAATGGCATTTGCCCTTGAAATAAATTAAGGAGACTGCTTTGATTTACTATCATAGTGAGGGTTCTTTGTGATGTAATTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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