Basic Information
VIS ID
TVIS44012509
Fusion event
HTLV-1-LINC00333 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
85117655/84543520 (Hg38)
End
85117655/84543520 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC00333
Nearest miRNA
hsa-mir-1297/Upstream/6845404; hsa-mir-1267/Downstream/3075145;
Nearest TSS
ENST00000623511/Upstream/661127; ENST00000446314/Downstream/18844;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/663758, chr13-CpG: 121/Downstream/3127794
Upstream sequence
taactataaaatataattaaatGTTAATGCTATCAGCAAGTTTTTTAATAAAATTCACTACCATTAAATTTTATATATCTCTAAGAAAATATAGTTGTAG
Downstream sequence
GTCACCATTAAAAATAGACATAACTGCAACTTTCTTTGaaagaaagaaagaaaaagaaaggcagagagagaatgatggaaaagggaagaaagagacagga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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