Basic Information
VIS ID
TVIS44012536
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
307280/307280 (Hg38)
End
307280/307280 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-6743/Upstream/97874; hsa-let-7a-2/Downstream/260809;
Nearest TSS
ENST00000527297/Upstream/7754; ENST00000533141/Downstream/351;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2901, chr11-CpG: 80/Downstream/3448
Nearby gene
IFITM2(+827) ;
Upstream sequence
GCTGTGTGGAGCGGGTCTGGGAGCCGTCACCCAGGTGGGCCTCCAGGGGAAAGGGCCATGGCTTCTAACTCCACCGTCCAGGTCTCTGCTATTGGCATCC
Downstream sequence
CACAGCCCCCTCTTCTGTCAGTGCTCCCAGAGTCCCCTTTCCTGGGCCTGGAGGGCTCCTTTGGGGCAGGCAACATTGGCCGCCAACCCTCTGACCTGCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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