Basic Information
VIS ID
TVIS44012547
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
61275127/60700993 (Hg38)
End
61275127/60700993 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA13B
Nearest miRNA
hsa-mir-1297/Upstream/5526445; hsa-mir-1267/Downstream/498805;
Nearest TSS
ENST00000623511/Upstream/15794; ENST00000414201/Downstream/216008;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/303082, chr13-CpG: 36/Downstream/3110593
Nearby gene
LINC00378(No orient, 5193)
Upstream sequence
CTAGCCCAAGCACTCAGTTTCTCTTTTCCATGGACAAAATGACATCAAATTTAAATTAAAAcactcttattaatgtcattctttggttaacctctgtctt
Downstream sequence
ctctactagactatgagctactgaatagcagatattgaatctgcttttgcttgccattttatctccagggccACATTAAAAAAAATTTTTTTGGAGAGTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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