Basic Information
VIS ID
TVIS44012549
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
108789200/108136852 (Hg38)
End
108789200/108136852 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1267/Upstream/605604; hsa-mir-4502/Downstream/2204106;
Nearest TSS
ENST00000623511/Upstream/266469; ENST00000375898/Downstream/77930;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/268137, chr13-CpG: 19/Downstream/77907
Nearby gene
LIG4(-70592) ;
Upstream sequence
AAGAATGAAACACAAATTTCACTTATGAGAAATAGTCAAATAGAGAAAAAAGTCTCTTAAAAAGAGATATCTAAAATAATAATAATCATGAGTAAAATAA
Downstream sequence
TACCCGACATCCTAAAAGTAGTAGATGTTAGAAAACAAAATCACTAAAGCAGATGACCTACATAGAGGCATATGTGATTCTTGTGTTGTCTAGTATTTCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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