Basic Information
VIS ID
TVIS44012553
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
85433294/84966950 (Hg38)
End
85433294/84966950 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1260a/Upstream/7700660; hsa-mir-1185-1/Downstream/8981276;
Nearest TSS
ENST00000550708/Upstream/1051900; ENST00000554753/Downstream/272524;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/3432860, chr14-CpG: 45/Downstream/563200
Upstream sequence
tctaggccagcctgggcaatgaaaggaaacccattcattaagaatataaaaaTAAAATATTTCAAATTGTCTAAAAAGGTATATTTCAGAGGTGGGTATG
Downstream sequence
TTATATATACATATAACAATATGTTTATACATTTTACATATATTACATTTTTGTATACATTATCTATCAATCTATCTAACATTAAATTATCTTTTCCTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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