VISDB Viral Integration Site DataBase

VIS ID

TVIS44012554

Fusion event

HTLV-1-DICER1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr14

Cytoband

q32.13

Reference genome

Start

End

95590031/95123694 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7a-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-519a-3p ; hsa-mir-374a-5p ; hsa-mir-154-5p ; hsa-mir-130a-3p ; hsa-mir-221-3p ; hsa-mir-222-3p ; hsa-mir-29a-3p ; hsa-mir-18a-5p ; hsa-mir-130b-3p ; hsa-mir-425-5p ; hsa-mir-29c-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-mir-296-3p ; hsa-mir-16-5p ; hsa-mir-3928-3p ; hsa-mir-497-5p ; hsa-mir-195-5p ; hsa-mir-9-5p ; hsa-mir-581 ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-106a-3p ; hsa-mir-4282 ; hsa-mir-1263 ; hsa-mir-376a-5p ; hsa-mir-586 ; hsa-mir-382-5p ; hsa-mir-218-5p ; hsa-mir-377-5p ; hsa-mir-21-5p ; hsa-mir-6800-5p ; hsa-mir-498 ; hsa-mir-548aw ; hsa-mir-582-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-3613-3p ; hsa-mir-101-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-152-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-301a-3p ; hsa-mir-4295 ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-5701 ; hsa-mir-8069 ; hsa-mir-1184 ; hsa-mir-3607-5p ; hsa-mir-4705 ; hsa-mir-7157-3p ; hsa-mir-6737-3p ; hsa-mir-5008-3p ; hsa-mir-6889-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-31-3p ; hsa-mir-200a-3p

Nearest miRNA

hsa-mir-1260a/Upstream/1175392; hsa-mir-1185-1/Downstream/14225;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/258836, chr14-CpG: 139/Downstream/33049

Nearest cancer related gene

DICER1(TSG, No orient, 0)

Upstream sequence

ttttttctagagacagggtttcgttgtgttgccccttgtgaactcaaacaatctacctgcctctggctcccaaagtgctggaattacaggcacaacccat

Downstream sequence

catgcccaaccTAGCCTTGAAAAGTTGAATCCATATTTTTAAGAGAAAAAAATCAACATTAAAAAATTAGTCACAATACCCAGATAAAATTTCTCCTAAG