Basic Information
VIS ID
TVIS44012567
Fusion event
HTLV-1-LOC105373444 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
16653763/16472495 (Hg38)
End
16653763/16472495 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105373444
Nearest miRNA
hsa-mir-3125/Upstream/3735051; hsa-mir-10b/Downstream/2875934;
Nearest TSS
ENST00000437798/Upstream/117310; ENST00000443066/Downstream/50681;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/458198, chr2-CpG: 50/Downstream/35600
Nearby gene
FAM49A(-76967) ;
Upstream sequence
tcctgacactgccaggtactctttccTTTATTCGACTATGTCTCACATCGGCAATGGAATCtgtgagagctgattttgtgtgttaacctgactgggctag
Downstream sequence
gaatggccaagaagctgggtgtgtctttgagggtttccagaaaagattagcattggaatcactagactgagaaaagaaactttccctcacccaattaatt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate