Basic Information
VIS ID
TVIS44012582
Fusion event
HTLV-1-NELFCD integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
57557186/58982131 (Hg38)
End
57557186/58982131 (Hg38)
Orient
+
Location type
Intronic
Target gene
NELFCD
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-375 ; hsa-mir-34a-5p ; hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-877-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/163818; hsa-mir-1-1/Downstream/1326343;
Nearest TSS
ENST00000382410/Upstream/856; ENST00000490205/Downstream/5579;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/409, chr20-CpG: 75/Downstream/24716
Upstream sequence
ACCTTACTCTAAagacccaactgaggcgcatgattgaaatgtagcttctcacgtccctcccctggagacggcccaacagttggtctggacgggagcctgg
Downstream sequence
gaacttgcatttttttttttttttttttttttttttttttttgtggtggagtttcgctcttgttgcccaggctggagtgtaatggcgccatcgcggctca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate