Basic Information
VIS ID
TVIS44012596
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
10422908/10421284 (Hg38)
End
10422908/10421284 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA4A
Nearest miRNA
hsa-mir-3138/Upstream/342592; hsa-mir-12113/Downstream/947543;
Nearest TSS
ENST00000502981/Upstream/304335; ENST00000505494/Downstream/35892;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/275577, chr4-CpG: 161/Downstream/35221
Nearby gene
ZNF518B(-18596) ;
Upstream sequence
gtgatctgcccacctcagcatcccaaagtgctgggattacaggcatgagccaccatgctggccgtcatctctgattttttttaagcagtgttttgtaatc
Downstream sequence
ctttttgcagagatgtttcacctctctagttagttgtgttcccaggtatcttatttttgttttttttttttggcttttgtgaatgggattgcattctaga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate