VISDB Viral Integration Site DataBase

VIS ID

TVIS44012598

Fusion event

HTLV-1-GUF1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

p12

Reference genome

Start

End

44694645/44692628 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-1277-5p ; hsa-mir-1273e ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-4785 ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-4635 ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4257 ; hsa-mir-3174 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4695-5p ; hsa-mir-216b-5p ; hsa-mir-6510-3p ; hsa-mir-6888-3p ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-1273a ; hsa-mir-31-5p ; hsa-mir-4522 ; hsa-mir-4696 ; hsa-mir-4486 ; hsa-mir-3120-5p ; hsa-mir-4432 ; hsa-mir-3664-5p ; hsa-mir-519d-5p ; hsa-mir-34c-3p ; hsa-mir-3145-5p ; hsa-mir-34b-3p ; hsa-mir-6507-3p ; hsa-mir-7977 ; hsa-mir-6773-3p ; hsa-mir-5187-3p ; hsa-mir-4267 ; hsa-mir-181a-2-3p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p ; hsa-mir-1227-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-5186 ; hsa-mir-550b-2-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p

Nearest miRNA

hsa-mir-12113/Upstream/4190509; hsa-mir-1243/Downstream/2960041;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/13904, chr4-CpG: 64/Downstream/33388

Upstream sequence

AAAATGAACATTGACATCTATAAAACTCCCACACAGTGCATGAATGTTAATGTTAACATGCAGAGACAAATTCCAGTGTTTAACAAACATGCTACAGTGA

Downstream sequence

CTTGGAAGTTTAACTTTATTTAATCATCTTGTCAGTGAAGAGAGTTAGCATATATAATTCTTCTTACCAAGGAATCTTCATGTTCCTTTGTATTGAGAAT