Basic Information
VIS ID
TVIS44012609
Fusion event
HTLV-1-LOC107986411 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
33438768/33438662 (Hg38)
End
33438768/33438662 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5A
Target gene
LOC107986411
Nearest miRNA
hsa-mir-10397/Upstream/1044187; hsa-mir-103a-1/Downstream/2709230;
Nearest TSS
ENST00000502646/Upstream/140752; ENST00000502508/Downstream/1957;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/724318, chr5-CpG: 55/Downstream/1867
Nearby gene
TARS(+2034) ;
Upstream sequence
aaagaaaaGGACTATTATTAAAATCAAGGTGTCAGCTAAAGAGCAGTtatatatatatacacacacacacacacacacacacatatgtatatgtgtatac
Downstream sequence
atatatatgtaATCTGCAAATTAGgtagctaatattgcataactctgttctcctagcaccttttcaagttacccttagcctttgtcaggacctcgctaga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate