Basic Information
VIS ID
TVIS44012643
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
81101117/79341360 (Hg38)
End
81101117/79341360 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-1265/Upstream/3788807; hsa-mir-107/Downstream/6923334;
Nearest TSS
ENST00000439456/Upstream/55907; ENST00000492149/Downstream/6109;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/97430, chr10-CpG: 83/Downstream/5966
Nearby gene
PPIF(+6103) ;
Upstream sequence
tggggattaagaaataatgttataaatccttaccatgtgcagtgtattaagtgcagcaaaaggtagctattcttattACCATAGTGCTTAtcttcttctt
Downstream sequence
cttcttctttttttttttttgagacagagtctcgctctgtcacccaggctggagtgcagtagctcgatctcagctcactgcaacctctgcctcctgggtt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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