Basic Information
VIS ID
TVIS44012649
Fusion event
HTLV-1-LOC105371793 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
43000767/44923399 (Hg38)
End
43000767/44923399 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105371793
Nearest miRNA
hsa-mir-1180/Upstream/715560; hsa-mir-10226/Downstream/11219;
Nearest TSS
ENST00000595228/Upstream/6462; ENST00000591013/Downstream/10577;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/11619, chr17-CpG: 61/Downstream/23891
Nearby gene
KIF18B(-1312) ;
Upstream sequence
taatatatgtgaaggccccaggaaatgggggatgttattcaaTTTGAatccaaccaacactcagtgaggcctcctgaggtcaaggcaccatgccagggca
Downstream sequence
ctgggggctacgatgatgtgaatctgtgactgcctctctggaaatcatggtacacagtgggggaaaACTTCATTAAGACTAATTGGAAAGGAGGGAACCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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