Basic Information
VIS ID
TVIS44012650
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q23
Reference genome
GRCh37/hg19
Start
77139492/79379492 (Hg38)
End
77139492/79379492 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/6526110;
Nearest TSS
ENST00000575820/Upstream/7102; ENST00000590224/Downstream/16364;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/291, chr18-CpG: 544/Downstream/14378
Nearby gene
ATP9B(+1210) ;
Upstream sequence
TCGGGGGTGGAGGCCAAGGGCAAATCAGAGGCTGCTCCCCCGTGCACCTTTAAAAGTAAACCACCCACCTGTGAAACTGACTAATAGAATAATAACATTG
Downstream sequence
TCGATAACCTCAGAAAAGCTGAACCCCTGAGCCTTTGGGAATAACACTGCAGTACAGCTTTCAGATACAGAAACGACCAGCCTTCGATCAGTTGGATCCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate