Basic Information
VIS ID
TVIS44012678
Fusion event
HTLV-1-KIF1C integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
End
4929660/5026365 (Hg38)
Orient
-
Location type
UTR3
Target gene
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-877-3p ; hsa-mir-769-3p ; hsa-mir-484 ; hsa-mir-149-5p ; hsa-let-7b-5p ; hsa-mir-1260b ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-4775 ; hsa-mir-203a-3p ; hsa-mir-4328 ; hsa-mir-4635 ; hsa-mir-590-3p ; hsa-mir-4694-3p ; hsa-mir-6513-5p ; hsa-mir-5089-5p ; hsa-mir-550b-2-5p ; hsa-mir-6728-5p ; hsa-mir-450b-3p ; hsa-mir-6807-5p ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-4745-3p ; hsa-mir-4455 ; hsa-mir-1538 ; hsa-mir-4252 ; hsa-mir-6889-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-665 ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6514-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4284 ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-323b-3p ; hsa-mir-4733-5p ; hsa-mir-6821-5p ; hsa-mir-24-3p ; hsa-mir-659-3p ; hsa-mir-29b-2-5p ; hsa-mir-6873-3p ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6817-3p ; hsa-mir-3927-5p ; hsa-mir-3675-3p ; hsa-mir-9-5p ; hsa-mir-640 ; hsa-mir-378a-5p ; hsa-mir-1193 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-2392 ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-122-5p ; hsa-mir-2276-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-2909 ; hsa-mir-1296-5p ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-4726-5p ; hsa-mir-4640-5p ; hsa-mir-4746-3p ; hsa-mir-764 ; hsa-mir-7160-3p ; hsa-mir-4512 ; hsa-mir-6895-5p ; hsa-mir-500a-5p ; hsa-mir-4777-3p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-6747-3p ; hsa-mir-3934-5p ; hsa-mir-125a-3p
Nearest miRNA
hsa-mir-1253/Upstream/56215; hsa-mir-10226/Downstream/1629075;
Upstream sequence
CAGGGAGACTCAATGTGAGCAAGAAAATGATAGAATACCAAGTTTTCTGGAGGTCAGAGGGAGCTGAGTTGAGTGTTACCGAGAATGCTGTGGGGTTTGA
Downstream sequence
GATGAGAAAAATAGCTTGCTAATTTAAAAGACGGATTATTTTTCCCTAAAGACCTTGACTTATGTAAATGTATATTATCCATAATTTTAAAAATCCACTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate