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TVIS44012678
Basic Information
VIS ID
TVIS44012678
Fusion event
HTLV-1-KIF1C integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
4929660/5026365 (Hg38)
End
4929660/5026365 (Hg38)
Orient
-
Location type
UTR3
Target gene
KIF1C
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-877-3p
;
hsa-mir-769-3p
;
hsa-mir-484
;
hsa-mir-149-5p
;
hsa-let-7b-5p
;
hsa-mir-1260b
;
hsa-mir-578
;
hsa-mir-526b-5p
;
hsa-mir-4775
;
hsa-mir-203a-3p
;
hsa-mir-4328
;
hsa-mir-4635
;
hsa-mir-590-3p
;
hsa-mir-4694-3p
;
hsa-mir-6513-5p
;
hsa-mir-5089-5p
;
hsa-mir-550b-2-5p
;
hsa-mir-6728-5p
;
hsa-mir-450b-3p
;
hsa-mir-6807-5p
;
hsa-mir-550a-5p
;
hsa-mir-550a-3-5p
;
hsa-mir-1271-3p
;
hsa-mir-4745-3p
;
hsa-mir-4455
;
hsa-mir-1538
;
hsa-mir-4252
;
hsa-mir-6889-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-665
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6514-3p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-4284
;
hsa-mir-6847-3p
;
hsa-mir-6811-3p
;
hsa-mir-214-5p
;
hsa-mir-323b-3p
;
hsa-mir-4733-5p
;
hsa-mir-6821-5p
;
hsa-mir-24-3p
;
hsa-mir-659-3p
;
hsa-mir-29b-2-5p
;
hsa-mir-6873-3p
;
hsa-mir-202-5p
;
hsa-mir-337-3p
;
hsa-mir-7162-5p
;
hsa-mir-516b-3p
;
hsa-mir-516a-3p
;
hsa-mir-6837-3p
;
hsa-mir-6754-3p
;
hsa-mir-412-3p
;
hsa-mir-1236-3p
;
hsa-mir-6515-3p
;
hsa-mir-6817-3p
;
hsa-mir-3927-5p
;
hsa-mir-3675-3p
;
hsa-mir-9-5p
;
hsa-mir-640
;
hsa-mir-378a-5p
;
hsa-mir-1193
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-2392
;
hsa-mir-575
;
hsa-mir-4676-5p
;
hsa-mir-6858-3p
;
hsa-mir-122-5p
;
hsa-mir-2276-3p
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-2909
;
hsa-mir-1296-5p
;
hsa-mir-675-5p
;
hsa-mir-4466
;
hsa-mir-4726-5p
;
hsa-mir-4640-5p
;
hsa-mir-4746-3p
;
hsa-mir-764
;
hsa-mir-7160-3p
;
hsa-mir-4512
;
hsa-mir-6895-5p
;
hsa-mir-500a-5p
;
hsa-mir-4777-3p
;
hsa-mir-6131
;
hsa-mir-3663-5p
;
hsa-mir-6747-3p
;
hsa-mir-3934-5p
;
hsa-mir-125a-3p
Nearest miRNA
hsa-mir-1253/Upstream/56215; hsa-mir-10226/Downstream/1629075;
Nearest TSS
ENST00000595228/Upstream/6272;
ENST00000318833/Downstream/9057;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/27862
,
chr17-CpG: 70/Downstream/51697
Upstream sequence
CAGGGAGACTCAATGTGAGCAAGAAAATGATAGAATACCAAGTTTTCTGGAGGTCAGAGGGAGCTGAGTTGAGTGTTACCGAGAATGCTGTGGGGTTTGA
Downstream sequence
GATGAGAAAAATAGCTTGCTAATTTAAAAGACGGATTATTTTTCCCTAAAGACCTTGACTTATGTAAATGTATATTATCCATAATTTTAAAAATCCACTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL175
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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