Basic Information
VIS ID
TVIS44012694
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
11529335/11529102 (Hg38)
End
11529335/11529102 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3691/Upstream/1089308; hsa-mir-10398/Downstream/4612454;
Nearest TSS
ENST00000381078/Upstream/41876; ENST00000379426/Downstream/9176;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/434668, chr6-CpG: 182/Downstream/8202
Nearby gene
TMEM170B(+9125) ;
Upstream sequence
cctcaaaagaagacatacaaatgggcaacaggtatgtgaaaaaatgttcaacatcactaatcatcagttacatgcaaaccaaaactacaatgagatatca
Downstream sequence
tctcacaccagttaaaatggcttttacccaaaagacaggcaataatgaacgatgggggaggatgtggaaaaaggggaacactcgtacactgttggtggga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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