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TVIS44012695
Basic Information
VIS ID
TVIS44012695
Fusion event
HTLV-1-ZNF451 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
56973023/57108225 (Hg38)
End
56973023/57108225 (Hg38)
Orient
+
Location type
UTR3
Target gene
ZNF451
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-124-3p
;
hsa-let-7e-5p
;
hsa-mir-4452
;
hsa-mir-183-3p
;
hsa-mir-526b-5p
;
hsa-mir-624-3p
;
hsa-mir-4790-3p
;
hsa-mir-548ax
;
hsa-mir-5582-3p
;
hsa-mir-548ao-5p
;
hsa-mir-548f-3p
;
hsa-mir-548e-3p
;
hsa-mir-548az-3p
;
hsa-mir-548ar-3p
;
hsa-mir-548a-3p
;
hsa-mir-6516-5p
;
hsa-mir-455-3p
;
hsa-mir-7641
;
hsa-mir-650
;
hsa-mir-3612
;
hsa-mir-4327
;
hsa-mir-6499-3p
;
hsa-mir-4695-3p
;
hsa-mir-1827
;
hsa-mir-4537
;
hsa-mir-1247-3p
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-1273e
;
hsa-mir-6799-5p
;
hsa-mir-6851-5p
;
hsa-mir-3689d
;
hsa-mir-6134
;
hsa-mir-4524a-3p
;
hsa-mir-219b-3p
;
hsa-mir-4329
;
hsa-mir-6865-5p
;
hsa-mir-6815-5p
;
hsa-mir-302f
;
hsa-mir-4666a-5p
;
hsa-mir-203a-3p
;
hsa-mir-4277
;
hsa-mir-9-3p
;
hsa-mir-584-3p
;
hsa-mir-3622b-3p
;
hsa-mir-3622a-3p
;
hsa-mir-6854-5p
;
hsa-mir-4429
;
hsa-mir-320d
;
hsa-mir-320c
;
hsa-mir-320b
;
hsa-mir-320a
;
hsa-mir-4465
;
hsa-mir-26b-5p
;
hsa-mir-26a-5p
;
hsa-mir-1297
;
hsa-mir-4756-3p
;
hsa-mir-5697
;
hsa-mir-5692a
;
hsa-mir-6830-5p
;
hsa-mir-4293
;
hsa-mir-4423-3p
;
hsa-mir-6787-5p
;
hsa-mir-663a
;
hsa-mir-1908-5p
;
hsa-mir-566
;
hsa-mir-4767
;
hsa-mir-6720-3p
;
hsa-mir-3188
;
hsa-mir-20b-3p
;
hsa-mir-3664-3p
;
hsa-mir-6499-5p
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-5690
;
hsa-mir-2114-5p
;
hsa-mir-5588-3p
;
hsa-mir-449c-5p
;
hsa-mir-34b-5p
;
hsa-mir-2682-5p
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-4695-5p
;
hsa-mir-510-5p
;
hsa-mir-512-5p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-7977
;
hsa-mir-6802-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-383-3p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-4474-3p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-4318
;
hsa-mir-5195-3p
;
hsa-mir-145-5p
;
hsa-mir-770-5p
;
hsa-mir-4712-5p
;
hsa-mir-1285-5p
;
hsa-mir-101-5p
;
hsa-mir-513c-3p
;
hsa-mir-513a-3p
;
hsa-mir-3606-3p
;
hsa-mir-6500-3p
;
hsa-mir-3614-5p
;
hsa-mir-1285-3p
;
hsa-mir-196a-3p
;
hsa-mir-3187-5p
;
hsa-mir-3613-3p
;
hsa-mir-371a-5p
;
hsa-mir-371b-5p
;
hsa-mir-372-5p
;
hsa-mir-373-5p
;
hsa-mir-4738-3p
;
hsa-mir-5189-5p
;
hsa-mir-548g-3p
;
hsa-mir-612
;
hsa-mir-616-5p
;
hsa-mir-6512-3p
;
hsa-mir-661
;
hsa-mir-6720-5p
;
hsa-mir-6860
;
hsa-mir-939-3p
Nearest miRNA
hsa-mir-10398/Upstream/3831154; hsa-mir-10524/Downstream/281907;
Nearest TSS
ENST00000381078/Upstream/5664;
ENST00000508548/Downstream/43932;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/17537
,
chr6-CpG: 91/Downstream/63931
Upstream sequence
acagtgcccggccTGTATTTGGTGATATTTTAAAAAATTCTACTTTGACCTTAAGTGCTTCAAGAATTGTGTTCAGTTAGTAGTCCTTTTGTAAGACTAA
Downstream sequence
CTTTCATATGCTATCTTTGCTCCATGAGCTATCATAGTACTGTTTTCTTTCATTACCCGTAAGAGTGGCTCTATCACAGCATTTACTGTTAAGGGCTACA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL175
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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