Basic Information
VIS ID
TVIS44012695
Fusion event
HTLV-1-ZNF451 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p12.1
Reference genome
End
56973023/57108225 (Hg38)
Orient
+
Location type
UTR3
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-let-7e-5p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-526b-5p ; hsa-mir-624-3p ; hsa-mir-4790-3p ; hsa-mir-548ax ; hsa-mir-5582-3p ; hsa-mir-548ao-5p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-7641 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-4327 ; hsa-mir-6499-3p ; hsa-mir-4695-3p ; hsa-mir-1827 ; hsa-mir-4537 ; hsa-mir-1247-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-1273e ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6134 ; hsa-mir-4524a-3p ; hsa-mir-219b-3p ; hsa-mir-4329 ; hsa-mir-6865-5p ; hsa-mir-6815-5p ; hsa-mir-302f ; hsa-mir-4666a-5p ; hsa-mir-203a-3p ; hsa-mir-4277 ; hsa-mir-9-3p ; hsa-mir-584-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-6854-5p ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-4756-3p ; hsa-mir-5697 ; hsa-mir-5692a ; hsa-mir-6830-5p ; hsa-mir-4293 ; hsa-mir-4423-3p ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-566 ; hsa-mir-4767 ; hsa-mir-6720-3p ; hsa-mir-3188 ; hsa-mir-20b-3p ; hsa-mir-3664-3p ; hsa-mir-6499-5p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6802-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-383-3p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-4474-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4318 ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-1285-5p ; hsa-mir-101-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-1285-3p ; hsa-mir-196a-3p ; hsa-mir-3187-5p ; hsa-mir-3613-3p ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-4738-3p ; hsa-mir-5189-5p ; hsa-mir-548g-3p ; hsa-mir-612 ; hsa-mir-616-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6860 ; hsa-mir-939-3p
Nearest miRNA
hsa-mir-10398/Upstream/3831154; hsa-mir-10524/Downstream/281907;
Upstream sequence
acagtgcccggccTGTATTTGGTGATATTTTAAAAAATTCTACTTTGACCTTAAGTGCTTCAAGAATTGTGTTCAGTTAGTAGTCCTTTTGTAAGACTAA
Downstream sequence
CTTTCATATGCTATCTTTGCTCCATGAGCTATCATAGTACTGTTTTCTTTCATTACCCGTAAGAGTGGCTCTATCACAGCATTTACTGTTAAGGGCTACA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate