Basic Information
VIS ID
TVIS44012698
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
154267756/153946621 (Hg38)
End
154267756/153946621 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/2843845; hsa-mir-1202/Downstream/906739;
Nearest TSS
ENST00000381078/Upstream/637639; ENST00000523520/Downstream/63875;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/814964, chr6-CpG: 33/Downstream/92830
Nearby gene
OPRM1(+63875) ;
Upstream sequence
TGCACACATCTTCTTTTGTACCCCTTCCAAGATCACAGAGAACTGAGATGATTTGAGAGGCTGGTTTCCACCATCTCCTTCTAATCATACACCACAACCC
Downstream sequence
CTTCCTAAGAACATGTATGCTCCTTTATACTCCACGGGAAACACCAAGGTGGCTGTGCAGATCCTGCAAATCAACAAACATTCAGCCTTCCATTAAGAGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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