Basic Information
VIS ID
TVIS44012716
Fusion event
HTLV-1-MIR4300HG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
82077683/82366641 (Hg38)
End
82077683/82366641 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
MIR4300HG
Nearest miRNA
hsa-mir-10392/Upstream/475805; hsa-let-7a-2/Downstream/3911692;
Nearest TSS
ENST00000527297/Upstream/266598; ENST00000526305/Downstream/37272;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2925481, chr11-CpG: 25/Downstream/322902
Upstream sequence
aaagtctgagaaactattatagtgaaggggagctgacagagacataatgaatacatataatgtggtactctggataagatccagattataaaaagaacat
Downstream sequence
taggaaaaaataaggaaatctgaataaagtgcagactttttaattaataataataaatccatattggttcattaattataataaatgtaccagtttgatg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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