Basic Information
VIS ID
TVIS44012723
Fusion event
HTLV-1-TMEM272 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
52394072/51819936 (Hg38)
End
52394072/51819936 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
TMEM272
Nearest miRNA
hsa-mir-15a/Upstream/267269; hsa-mir-1267/Downstream/990114;
Nearest TSS
ENST00000623511/Upstream/15639; ENST00000242819/Downstream/25214;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/15499, chr13-CpG: 118/Downstream/191242
Upstream sequence
AATGGTCACTGAATCCGTCTTTTGGAAACTGTCTTTTAACATGACCCTCAGTAACAAATACATTTTATGCCAGGTCCTAGTCACTgggtaactgcatgtc
Downstream sequence
cttgttggcttagagaagtcctggtttatgctgttgctctggcaggatgattattagagcccccttgtactctcaaaagtgtcccagttaggatgataaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate