Basic Information
VIS ID
TVIS44012724
Fusion event
HTLV-1-LOC101927072 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
68609514/68035382 (Hg38)
End
68609514/68035382 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B
Target gene
LOC101927072
Nearest miRNA
hsa-mir-1297/Upstream/1817058; hsa-mir-1267/Downstream/9662630;
Nearest TSS
ENST00000623511/Upstream/662995; ENST00000627910/Downstream/842998;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/804055, chr13-CpG: 34/Downstream/949390
Nearby gene
LINC00364(No orient, 655388)
Upstream sequence
caaaccatgtcacatcttggtggcttaaatgacaatttattattatcttgaagggtttcataggttaacttggcacagctggtggtacttgcttgggtcg
Downstream sequence
ctcatgaaattgcaaacagattgcatctgaggctggaatcccttgaatgctcaactggtctggacatgccagatggtcggctcaaaataccaacaattga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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